The results of the tests used to diagnose nasopharyngeal cancer are often also used to stage the disease. Some people, especially if the cancer is advanced, might not want to be treated at all. Patients may want to think about taking part in a clinical trial. Immunotherapy is a newer option to treat some of these cancers, either alone or along with chemo. This “devastating treatments” greatly kill cancer cells, but they cannot just only target to the local tumor. If cancer is still in the lymph nodes after this treatment, surgery (neck dissection) may be done to remove the lymph nodes. It cannot be given by the National Cancer Institute. Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan. Whether you or someone you love has cancer, knowing what to expect can help you cope. Your cancer care team will recommend treatment options depending on the stage – the extent of the cancer in the nasopharynx and if and how far the cancer has spread. These tests are sometimes called follow-up tests or check-ups. The chemo drug most often used is cisplatin, but sometimes it's given along with another drug. Treatment of nasopharyngeal carcinoma depends on many factors like location of the tumor, its stage and the general health condition of the patient. The summaries are reviewed regularly and changes are made when there is new information. It is usually part of the standard treatment for early stage nasopharyngeal cancer. This is called chemoradiation. Talk with your doctor if you think you may be at risk. Also Read: Oral Cancer: Causes, Symptoms And Treatment PDQ Nasopharyngeal Cancer Treatment (Adult). Sometimes, the pathologist’s review results in a change to the stage of the cancer and more treatment after surgery. The type of nasopharyngeal cancer (1) The stage of cancer whether it is localized or spread to other parts of the body Increased level of EBV antibodies and EBV-DNA markers in the blood before the start of treatment and after the end of treatment The time duration between biopsy and beginning of the radiation therapy. The usual treatment is chemo, often with cisplatin and one other drug. Still, they're not right for everyone. After nasopharyngeal cancer has been diagnosed, tests Information about clinical trials is available from the NCI website. It cannot be identified as an NCI PDQ cancer information summary unless the whole summary is shown and it is updated regularly. These types of radiation therapy include the following: The way the radiation therapy is given depends on the type and stage of the cancer being treated. Doctors call this part of cancer treatment “palliative care" or "supportive care.” It is an important part of your treatment plan, regardless of your age or the stage of disease. In stage IVB: Cancer has spread beyond the lymph nodes in the neck to distant lymph nodes, such as those between the. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment. Importance: Since the advent of modern radiotherapy techniques and incorporation of systemic chemotherapy for nasopharyngeal cancer, locoregional control has been excellent. The following tests and procedures may be used: The prognosis (chance of recovery) and treatment options depend on The cancer. the following: These and other signs and symptoms may be caused by nasopharyngeal cancer or by other conditions. Three types of standard treatment are used: New types of treatment are being tested in clinical The main treatment for nasopharyngeal cancer is radiation therapy, often combined with chemotherapy. You might also need to have chemotherapy (medicines used to treat cancer). cancer may include the following: Treatment of recurrent EnlargeAnatomy of the pharynx (throat). Cancer has spread to the parapharyngeal space and/or nearby muscles. It’s important to weigh the benefits of each treatment option against the possible risks and side effects. Many cancers of the nasopharynx can be cured, especially if they are found early. It does not give formal guidelines or recommendations for making decisions about health care. This is a specialized surgery that should only be done by a surgeon with a great deal of experience with it, so it’s not available at all medical centers. … Nasopharyngeal cancer most commonly Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment. Importance Since the advent of modern radiotherapy techniques and incorporation of systemic chemotherapy for nasopharyngeal cancer, locoregional control has been excellent. However, a user would be allowed to write a sentence such as “NCI’s PDQ cancer information summary about breast cancer prevention states the risks in the following way: [include excerpt from the summary].”. If you’ve been diagnosed with nasopharyngeal cancer (NPC), your treatment team will discuss your options with you. In stage I, cancer has formed and the cancer: In stage II, one of the following is true: In stage III, one of the following is true: Stage IV is divided into stages IVA and IVB. Clinical trials are carefully controlled research studies that are done to get a closer look at promising new treatments or procedures. Having a risk factor does not mean that you will Treatment options for Nasopharyngeal Cancer. Available at: https://www.cancer.gov/types/head-and-neck/patient/adult/nasopharyngeal-treatment-pdq. Learn more about these partnerships and how you too can join us in our mission to save lives, celebrate lives, and lead the fight for a world without cancer. External radiation therapy to the thyroid or the pituitary gland may change the way the thyroid If the cancer is removed by surgery, a pathologist will examine a sample of the cancer tissue under a microscope. Treatment of stage IV nasopharyngeal cancer may include the following: Chemotherapy given with radiation therapy, followed by more chemotherapy. Some clinical trials are open only to patients who have not started treatment. the following: Other factors that may affect prognosis include: The process used to find out whether cancer has spread within the nasopharynx or to other parts of the body is called staging. The affected lymph nodes are larger than 6 centimeters and/or are found in the lowest part of the neck. nasopharyngeal cancer may include the NIH is the federal government’s center of biomedical research. It is intended to help you and your family make informed decisions, together with your doctor. with cancer. cancer may include the following: Treatment of stage IV nasopharyngeal The usual treatment for these early stage cancers is radiation therapy aimed at the tumor. Recurrent nasopharyngeal Ask your cancer care team questions. "The cure rate after treatment for stage 3 nasopharyngeal cancer (nose cancer) is only 60 percent and it drops to below 50 percent in stage 4." Radiation Therapy for Nasopharyngeal Cancer, Targeted Therapy for Nasopharyngeal Cancer, Treatment Options by Stage of Nasopharyngeal Cancer, Health Professionals Associated with Cancer Care, Questions to Ask About Nasopharyngeal Cancer, Thinking about taking part in a clinical trial, Considering complementary and alternative methods, Find Support Programs and Services in Your Area, Choosing to stop treatment or choosing no treatment at all, Making Strides Against Breast Cancer Walks, Facts & Figures 2021 Reports Another Record-Breaking 1-Year Drop in Cancer Deaths. line the nasopharynx. Most people with NPC get a combination of radiation and chemotherapy. Accessed . For information about side effects caused by treatment for cancer, see our Side Effects page. A second opinion can give you more information and help you feel more confident about the treatment plan you choose. In the case of permitted digital reproduction, please credit the National Cancer Institute as the source and link to the original NCI product using the original product's title; e.g., “Nasopharyngeal Cancer Treatment (Adult) (PDQ®)–Patient Version was originally published by the National Cancer Institute.”. The cancer may come through the pharynx on the way to the trachea or the esophagus. NCCN Clinical Practice Guidelines in Oncology. Nasopharyngeal cancer (NPC) in children is treated largely the same way as NPC in adults. These might include nursing or social work services, financial aid, nutritional advice, rehab, or spiritual help. Call our National Cancer Information Center at 1-800-227-2345 and speak with one of our trained specialists. Remember that even if you choose not to treat the cancer, you can still get supportive care to help with pain or other symptoms. Clinical trials are part of the cancer research process. This is also a good time to consider if you would like a second opinion. Patients can enter clinical trials before, during, or after starting their cancer treatment. cancer is usually radiation Both versions have cancer information that is accurate and up to date and most versions are also available in Spanish. The American Cancer Society couldn’t do what we do without the support of our partners. © 2021 American Cancer Society, Inc. All rights reserved. These abnormal cells may become cancer and spread into nearby normal tissue. A high level of EBV antibodies and EBV-DNA markers in the blood before and after treatment. Cancer has also spread to one or more lymph nodes on both sides of the neck. Tissue. The disease is metastatic nasopharyngeal cancer, not lung cancer. This PDQ cancer information summary has current information about the treatment of adult nasopharyngeal cancer. The results of these tests can show if your condition has changed or if the cancer has recurred (come back). General information about clinical trials is also available. If chemo has been given already, different chemo drugs may be tried. Complementary methods refer to treatments that are used along with your regular medical care. The PDQ database contains summaries of the latest published information on cancer prevention, detection, genetics, treatment, supportive care, and complementary and alternative medicine. Lymph system. Many of today's standard treatments for cancer are based on earlier clinical trials. Cancer cells break away from where they began (the primary tumor) and travel through the lymph system or blood. Patients with these stages of NPC usually get chemoradiation (chemotherapy given along with radiation therapy) to the nasopharynx and neck lymph nodes. Recurrence can be local (in or near the same place it started) or distant (spread to organs such as the lungs or bone). The nostrils Descriptions of the common types of treatments used for NPC are listed below. Information about using the images in this summary, along with many other images related to cancer can be found in Visuals Online. Chemotherapy drugs. The American Cancer Society medical and editorial content team. It’s important to understand what the side effects are likely to be before starting this treatment. You may feel that you need to make a decision quickly, but it’s important to give yourself time to absorb the information you have learned. Some of the tests that were done to diagnose the cancer or to find out the stage of the cancer may be repeated. Some treatments are standard (the currently used treatment), and some NPC differs significantly from other cancers of the head and neck in its occurrence, causes, clinical behavior, and treatment. It's important to understand the goal of any further treatment – whether it's to try to cure the cancer, to slow its growth, or to help relieve symptoms – as well as the likelihood of benefits and risks. 4/F., Champion Tower, 3 Garden Road, Central, Hong Kong Unit. [PMID: 26389409]. Different types of programs and support services may be helpful, and can be an important part of your care. treatment may become the standard treatment. Nasopharyngeal Carcinoma can be defined as the proliferation of cancer cells, in the tissues of the nasopharynx, i.e. Chemotherapy plus the targeted drug cetuximab (Erbitux) or immunotherapy may be other options. Nasopharyngeal carcinoma (NPC), or nasopharynx cancer, is the most common cancer originating in the nasopharynx, most commonly in the postero-lateral nasopharynx or pharyngeal recess (fossa of Rosenmüller), accounting for 50% of cases.NPC occurs in children and adults. cells form in the tissues of the nasopharynx. These NPCS have spread to distant parts of the body and can be hard to treat. Depending on the stage of the cancer, your overall health, and other factors, your treatment options may include: Surgery for Nasopharyngeal Cancer Radiation Therapy for Nasopharyngeal Cancer It is a rare type of Head and Neck Cancer, and also known as Nasopharyngeal carcinoma. Cancer has spread to one or more lymph nodes on one or both sides of the neck. Chemotherapy may be given after radiation therapy to kill any cancer cells that are left. There are different types of treatment for patients with nasopharyngeal Stage IV Nasopharyngeal Cancer. National Comprehensive Cancer Network. Signs of nasopharyngeal cancer include trouble Tests and procedures to detect, diagnose, and stage nasopharyngeal cancer are done before planning treatment. The nasopharynx is the Alternative treatments are used instead of a doctor’s medical treatment. Learn more about newly diagnosed and recurrent nasopharyngeal cancer in this expert-reviewed summary. Most summaries come in two versions. There are three ways that cancer spreads in the body. Recurrent NPC in regional (neck) lymph nodes can sometimes be treated with radiation therapy. Another option in some cases is to give chemoradiation as the first treatment. Risk factors for nasopharyngeal cancer include Some NPCs diagnosed before the current staging system was in place may have been given the stage IVC. These methods can include vitamins, herbs, and special diets, or other methods such as acupuncture or massage, to name a few. and lymph nodes in the neck. Editorial Boards write the PDQ cancer information summaries and keep them up to date. Whether or not you continue treatment, there are still things you can do to help maintain or improve your quality of life. The affected lymph nodes are 6 centimeters or smaller. The affected lymph nodes are 6 centimeters or smaller. not get cancer. These NPCS have spread to distant parts of the body and can be hard to treat. Some of the tests will continue to be done from time to time after treatment has ended. It’s important to discuss all treatment options, including their goals and possible side effects, with your doctors to help make the decision that best fits your needs. Read on for more information on nasopharyngeal cancer symptoms, signs and diagnosis. Whether you want to learn about treatment options, get advice on coping with side effects, or have questions about health insurance, we’re here to help. Check with your doctor if you have any of the following: Procedures that make pictures of the nose and throat help diagnose nasopharyngeal cancer. It can be hard to cope if treatment has changed your appearance, voice or how you eat and drink. Nasopharyngeal Cancer: What is it. The cancer travels through the, Lymph system. Cancer can spread through tissue, the lymph system, and the blood: When cancer spreads to another part of the body, it is called metastasis. Be sure to talk to your cancer care team about any method you are thinking about using. It is common to feel overwhelmed by different feelings. Some clinical trials are open only to patients who have not started treatment. Certain factors affect prognosis (chance of recovery) and treatment options. Some tests will be repeated in order to see how well the treatment is working. Radiotherapy is the best treatment option … There are two types of radiation therapy: Certain ways of giving radiation therapy can help keep radiation from damaging nearby healthy tissue. Experts agree that the best way to treat NPC in the more advanced stages is in a clinical trial. This may shrink the cancer and help to control any symptoms the cancer is causing. More information on insurance coverage is available on Cancer.gov on the Managing Cancer Care page. A clinical trial is a study to answer a scientific question, such as whether one treatment is better than another. The cells lining the nasopharynx can become cancerous and give rise to nasopharyngeal cancer, more commonly known as nose cancer. The cancer spreads from where it began by growing into nearby areas. of the nasopharynx. The best way to cite this PDQ summary is: PDQ® Adult Treatment Editorial Board. This is usually followed by more chemo, most often with cisplatin plus 5-FU. If you have nasopharyngeal cancer, your healthcare team will create a treatment plan just for you. This is preventive (prophylactic) radiation. When clinical trials show that a new treatment is better than the Radiation and chemotherapy can make you feel tired and sick to your stomach. The treatment plan for nasopharyngeal cancer depends on the size, location, extent of the disease, and the patient’s health. into an ear. If there's no sign of the cancer after chemo, either radiation therapy to the nasopharynx and the lymph nodes in the neck or chemoradiation is given to try to kill any remaining cancer cells. The information gathered from the staging process determines the stage of the disease. For some patients, taking part in a clinical trial may be the best treatment choice. The following stages are used for nasopharyngeal affect the risk of nasopharyngeal cancer. Some clinical trials only include patients who have not yet received treatment. These Boards are made up of experts in cancer treatment and other specialties related to cancer. If the cancer recurs in distant sites, options might include chemotherapy or immunotherapy (or both). cancer is cancer that has recurred Your feelings after nasopharyngeal cancer treatment For some people, it takes several months to recover from treatment. Trials are based on past studies and what has been learned in the laboratory. Another option in some cases is to give chemoradiation as the first treat… Research. Help make it a reality. standard treatment, the new March 1, 2018. More information about contacting us or receiving help with the Cancer.gov website can be found on our Contact Us for Help page. But adding chemo leads to more side effects, which can affect quality of life. From basic information about cancer and its causes to in-depth information on specific cancer types – including risk factors, early detection, diagnosis, and treatment options – you’ll find it here. The main treatment for nasopharyngeal cancer is radiotherapy. How nasopharyngeal cancer is treated. Images in this summary are used with permission of the author(s), artist, and/or publisher for use in the PDQ summaries only. therapy to the tumor Stage 0 is also called carcinoma in situ. Questions can also be submitted to Cancer.gov through the website’s E-mail Us. breathing, speaking, or hearing. therapy. External and internal radiation therapy are used to treat nasopharyngeal cancer. The process used to find out if cancer cells have spread to other parts of the body is called staging. Radiation therapy is a cancer treatment that uses high-energy x-rays or other types of radiation to kill cancer cells or keep them from growing. The NCI is part of the National Institutes of Health (NIH). Complementary & Alternative Medicine (CAM), Coping with Your Feelings During Advanced Cancer, Emotional Support for Young People with Cancer, Young People Facing End-of-Life Care Decisions, Late Effects of Childhood Cancer Treatment, Tech Transfer & Small Business Partnerships, Frederick National Laboratory for Cancer Research, Milestones in Cancer Research and Discovery, Step 1: Application Development & Submission, Childhood Esthesioneuroblastoma Treatment, Childhood Nasopharyngeal Cancer Treatment, Childhood Salivary Gland Tumors Treatment, Metastatic Squamous Neck Cancer with Occult Primary Treatment, Paranasal Sinus & Nasal Cavity Cancer Treatment, Oral Cavity, Pharyngeal, and Laryngeal Cancer Prevention, Oral Cavity, Pharyngeal, and Laryngeal Cancer Screening, General Information About Nasopharyngeal Cancer, Treatment Options for Recurrent Nasopharyngeal Cancer, To Learn More About Nasopharyngeal Cancer, Oral Complications of Chemotherapy and Head/Neck Radiation, Chemotherapy and You: Support for People With Cancer, Radiation Therapy and You: Support for People With Cancer, Questions to Ask Your Doctor about Cancer, https://www.cancer.gov/types/head-and-neck/patient/adult/nasopharyngeal-treatment-pdq, U.S. Department of Health and Human Services. 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